Jevtana (cabazitaxel) injection is an anti-neoplastic agent that belongs to the taxane grade standing for intravenous usage. It is formulated by semi-synthesis with a substance excerpted from yew needles. Cabazitaxel is an almost-white powder that comes with a molecular formula of C45H57NO14 .C3H6O and has a molecular weight of 894.01 (for the acetone solvate) / 835.93 (for the solvent free). It is lipotropic, practically indissoluble in water and soluble in alcohol.
The injection is a non-pyrogenic, sterile, clear yellow to brownish-yellow syrupy intermixture and is accessible in single-dose vials incorporating 60 mg cabazitaxel (anhydrous and solvent free) and 1.56 g polysorbate 80. Each mL incorporates 1.04 g polysorbate 80 and 40 mg cabazitaxel (anhydrous). This is a clear, neutral, sterile, and non-pyrogenous solution that contains 13% (w/w) ethanol in water for injection, close to 5.7 mL.
- Muscle pains
- Flu symptoms
- Sores in the throat and mouth
- Fast and shallow breathing
- Pale skin
- Shortness of breath, feeling light-headed
- Speedy heart rates
- Trouble in concentration
- Severe or ongoing diarrhea
Before receiving cabazitaxel, inform the doctor or pharmacist if you are hypersensitive to it; or to polysorbate 80; or if you have some other allergic reactions. This product may incorporate other inactive ingredients, that can reason in allergic reactions or other problems. Talk to the druggist for more details.
Before taking this medication, inform the doctor or pharmacist your medical history, particularly of: blood/bone marrow statuses (such as , neutropenia, thrombocytopenia, bone marrow suppression, anemia), stomach/abdominal difficulties (such as bleeding, ulcers, blockage), liver disease, recent/current contagions.