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MYSOLINE 250MG - PRIMIDONE

MYSOLINE 250MG - PRIMIDONE
MYSOLINE 250MG - PRIMIDONE
Product Code : 054
Product Description

MYSOLINE 250MG - PRIMIDONE

Primidone - Primidone is an anti-epileptic drug, also called an anticonvulsant.

Primidone is used to control seizures.

Primidone may also be used for other purposes not listed in this medication guide.

Pharmacology: Primidone and its metabolites  have anticonvulsant activity, raising seizure threshold and altering seizure patterns.

Indication: Control of grand mal, psychomotor, or focal epileptic seizures; may control grand mal seizures refractory to other anticonvulsants.

Unlabeled Uses

Treatment of benign familial tremor (essential tremor).

 Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity.

Oral Generalised tonic-clonic seizures

Adult: Initially, 125 mg daily at bedtime, increased by 125 mg every 3 days if necessary up to 500 mg daily, given in 2 divided doses, may further increase by 250 mg every 3 days if needed.

Maintenance: 0.75-1.5 g daily.

Child: Initial dose: 125 mg daily, may increase by 125 mg every 3 days if needed.

Maintenance: >9 yr: Same as adult dose; 6-9 yr: 0.75-1 g daily; 2-5 yr: 500-750 mg daily; <2 yr: 250-500 mg daily. Oral Partial seizures

Adult: Initially, 125 mg daily at bedtime, increased by 125 mg every 3 days if necessary up to 500 mg daily, given in 2 divided doses, may further increase by 250 mg every 3 days if needed.

Maintenance: 0.75-1.5 g daily.

Child: Initial dose: 125 mg daily, may increase by 125 mg every 3 days if needed.

Maintenance: >9 yr: Same as adult dose; 6-9 yr: 0.75-1 g daily; 2-5 yr: 500-750 mg daily; <2 yr: 250-500 mg daily. Oral Essential tremor

Adult: Initially, 50 mg daily gradually increased over 2-3 wk if necessary. Max dose: 750 mg daily.

Indications:

Adult: PO Generalised tonic-clonic seizures; Partial seizures Initial: 125 mg at bedtime, increased by 125 mg every 3 days if needed up to 500 mg/day in 2 divided doses, may further increase if needed.

Maintenance: 0.75-1.5 g/day. Essential tremor Initial: 50 mg/day, then increase over 2-3 wk if needed. Max: 750 mg/day.

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