Why Is it Used ?
BUDESONIDE :Adult: PO Inflammatory bowel disease Active: 9 mg/day, up to 8 wk. Maintenance: 6 mg once daily, up to 3 mth. Inhalation Asthma As metered dose inhaler: 400 mcg/day in 2 divided doses, up to 1.6 mg/day in severe cases. Maintenance: 200-400 mcg/day. As dry powd inhaler: 200-800 mcg/day. As nebulised soln: Inhale 1-2 mg twice daily.
Maintenance: 0.5-1 mg twice daily. Nasal Prophylaxis and treatment of rhinitis Initial: 200 mcg into each nostril daily, may reduce to 100 mcg into each nostril daily until symptoms are controlled. Nasal polyps 100 mcg twice daily into each nostril for up to 3 mth.
What are the Side Effects ?
BUDESONIDE :Loss of skin collagen and SC atrophy; local hypopigmentation of deeply pigmented skin; dryness, irritation, epistaxis, rarely ulceration or perforation of the nasal septum; smell and taste disturbances; hoarseness and candidiasis of the mouth or throat.
What Precautions should be taken ?
BUDESONIDE :Active or doubtfully quiescent tuberculosis, paradoxical bronchospasm; children, elderly; pregnancy, lactation.
Do not take this if you have any of the below ...
BUDESONIDE :Hypersensitivity. Acute infections uncontrolled by antimicrobial chemotherapy.