Alphadol 0.25mg Alfacalcidol Capsules

Alphadol 0.25mg Alfacalcidol Capsules

79/sTRIP INR

Product Details:

  • Drug Type General Medicines
  • Physical Form Tablets
  • Dosage 0.25 mcg
  • Suitable For Adults
  • Supply Ability : 10000000 Piece Per Week
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Price And Quantity

  • 79/sTRIP INR
  • 10000000 Piece

Product Specifications

  • 0.25 mcg
  • Adults
  • General Medicines
  • Tablets

Trade Information

  • Cash in Advance (CID), Cash Advance (CA)
  • 10000000 Piece Per Week
  • 1 Week
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia

Product Description

DESCRIPTION
Alphadol
Red, transparent, round, soft gelatin capsules, containing pale yellow coloured clear oily liquid.
Alphadol-1
Green, transparent, round, soft gelatin capsules, containing pale yellow colored clear oily liquid.
 
COMPOSITION
Alphadol
Each soft gelatin capsule contains :
Alfacalcidol BP. 0.25 mcg (1α-hydroxyvitamin D3)
Approved colours used in capsule shells.
Alphadol-1
Each soft gelatin capsule contains :
Alfacalcidol BP. 1mcg (1α-hydroxyvitamin D3)
Colours: Brilliant Blue & Tartrazine
 
PHARMACOLOGY Alfacalcidol is fat soluble and upto 100% absorption normally takes place. After absorption,
alfacalcidol is rapidly hydroxylated at 2 position, predominantly in liver although the enzyme is
widely distributed in body tissues.1 Alfacalcidol (1α-hydroxyvitamin D3) undergoes rapid hepatic
conversion to 1,25-dihydroxyvitamin D3, which acts as a regulator of calcium and phosphate
metabolism. Due to this rapid conversion, the therapeutic benefits of alfacalcidol are virtually the
same as those of 1,25-dihydroxyvitamin D3.
2 The main effects are to increase circulating 1,25-
dihydroxyvitamin D3 levels, and thereby to increase intestinal absorption of calcium and
phosphate, promote bone mineralisation, regulate plasma parathyroid hormone levels as well as
to decrease bone resorption, with relief of bone and muscle pain.


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